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Best vitamin D supplements (UK) 2026: Top picks by dose, form and diet (D3 vs D2)

By: Andrew Forrest - February 2026

Best vitamin D supplements

Which vitamin D should you take in the UK? Doses from 400-4,000 IU, safety limits, formats, and what the evidence actually shows and D3 vs D2.

Table of contents 

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Vitamin D is one of the few nutrients whose levels are significantly affected by location and season. At UK latitudes, winter sunlight is too weak to support meaningful vitamin D production in the skin, which is why public health guidance emphasises supplementation during autumn and winter.[1][2][3]

Health & Wellness Disclaimer

The information in this article is provided for general educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. While we reference peer-reviewed research and official UK and international guidance, nutritional needs vary between individuals, and supplement decisions should take into account personal medical history, current medications, and professional advice.

Vitamin D supplementation may not be appropriate for everyone. You should speak to a qualified healthcare professional before starting or increasing vitamin D if you have kidney disease, hyperparathyroidism, sarcoidosis, a history of kidney stones, disorders affecting calcium metabolism, are pregnant or breastfeeding, or are taking medications that affect calcium or vitamin D balance. High doses taken over time can cause adverse effects, including elevated blood calcium levels.

Product availability, formulations and labelling can change, and it is your responsibility to check the manufacturer's instructions and dosage guidance before use. Walks4all does not provide personalised medical advice, and reliance on any information in this article is at your own discretion.


UK seasonal vitamin D infographic comparing summer vs winter sunlight and explaining why vitamin D production drops in autumn and winter

Vitamin D's most established benefits are support for bones, teeth and muscles, because it helps regulate calcium and phosphate.[1] If levels drop too low, deficiency diseases can follow, including rickets in children and osteomalacia in adults. That's why vitamin D is often seen as a 'foundational' supplement rather than a quick fix.[1][3]

Photorealistic UK winter walk showing low sunlight months when vitamin D levels can drop and supplementation is commonly recommended

This guide helps you choose the best vitamin D supplement for you - by dose, format (tablet, softgel, spray, liquid, gummy), and diet.

What we'll cover in this Best vitamin D supplements guide

  • Best vitamin D supplements by dose band (low → high)
  • What vitamin D does in the body (and why deficiency matters)
  • Health benefits of Vitamin D
  • D3 vs D2: What's the difference and which to choose
  • UK dosing guidelines
  • When to take it, storage, safety, and who should check with a clinician
  • Why D3 is sometimes combined with K2 (and when you might use D3 alone)

Vitamin D dose bands infographic with 400IU, 1000IU, 2000IU, 2500IU and 4000IU to help choose a daily vitamin D supplement dose in the UK

Quick comparison table (best picks at a glance)

Name Dose (daily) Type Vegan Snapshot
Natures Aid Vitamin D3 10μg 400 IU (10μg) Tablet Yes A baseline daily dose for simple maintenance.
Solgar Vitamin D3 400 IU 400 IU (10μg) Softgel No Small softgel format if you prefer capsules to tablets.
Solgar Vitamin D3 1,000 IU 1,000 IU (25μg) Softgel No A popular daily top-up dose in an easy-to-swallow softgel.
Vitabiotics Ultra Vitamin D 1,000 IU 1,000 IU (25μg) Tablet No One-a-day D3 tablet for simple daily cover.
Bioglan Vitamin D3 VitaGummies 1,000 IU 1,000 IU (25μg) Gummy No Great if tablets are the barrier and you want easy compliance.
Bassetts Adult Vitamin D Pastilles 1,000 IU (25μg) Pastille No A simple one-a-day chewable option.
Vitabiotics Ultra Vitamin D 2,000 IU 2,000 IU (50μg) Tablet No A common winter-strength dose in a straightforward tablet.
Natures Aid Vitamin D3 Liquid 2,500 IU 2,500 IU (62.5μg) Liquid Yes Vegan liquid D3 if you prefer drops over pills.
Zipvit Vitamin D3 4,000 IU 4,000 IU (100μg) Tablet No Upper-limit band tablet for adults who want a high daily dose.
VitaBright Vitamin D3 4,000 IU 4,000 IU (100μg) Softgel No Upper-limit band in a softgel.
BetterYou Vitamin D3 4,000 IU Oral Spray 4,000 IU (100μg) Oral spray No Upper-limit band spray if you don't want pills.
Novomins Vitamin D3 Gummies 4,000 IU 4,000 IU (100μg) Gummy No High-strength gummy option (label-check essential).
Zenement Vitamin D3 + K2 2,000 IU + K2 (150μg) Softgel No Mid-strength D3 with K2 (MK-7) in one daily softgel.
Zipvit Vitamin D3 + K2 MK-7 4,000 IU + K2 (100μg) Tablet No High-strength D3 + K2 combo in one daily tablet.

Always check labels for dose.

Best vitamin D supplements by strength (low → high)

There isn't a 'best' vitamin D supplement, as what works for one person may be too low or too high a dose for another. So, we have split our recommendations into different dosage ranges. We cover which dose may work for you after these 'best of' choices.

Decision infographic comparing vitamin D supplement formats tablet, softgel, spray, liquid and gummy to help choose the easiest option to take daily

Also, vitamin D is available in various forms (tablets, softgels, gummies and liquids/sprays), so we have included a range of options in each dosage band.

400 IU (10μg): the UK baseline dose

Natures Aid Vitamin D3 10μg (400 IU) tablets

Natures Aid Vitamin D3 10μg (400 IU) tablets
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Natures Aid Vitamin D3 10μg (400 IU) tablets - features
Natures Aid Vitamin D3 10μg (400 IU) tablets - directions
Natures Aid Vitamin D3 10μg (400 IU) tablets - size
  • Dose: 400 IU (10μg) per tablet
  • How to take: 1 daily, ideally with food
  • Always check the label for dose and strength

This is a simple daily vitamin D3 tablet for maintenance, the type of dose many people use as a 'winter cover' in the UK. Baseline daily intakes are the core public health approach: sufficient to reduce the risk of low status without entering high-dose territory.[2][3]

We found the tablets easy to take daily, with no fuss - ideal if you just want a reliable low dose you'll actually stick to.


Solgar Vitamin D3 400 IU (10μg) softgels

Solgar Vitamin D3 400 IU (10μg) softgels
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Solgar Vitamin D3 400 IU (10μg) softgels - features
Solgar Vitamin D3 400 IU (10μg) softgels - directions
  • Dose: 400 IU (10μg) per softgel
  • How to take: 1 daily with a meal
  • Always check the label for dose and strength

This is the same baseline dose, but in a softgel format for those who prefer capsules to tablets. Vitamin D is fat-soluble, and taking it with a meal is a practical way to support absorption.[6]

We found the softgels particularly easy to swallow, making them a good option if 'tablet fatigue' prevents you from taking them consistently.


1,000 IU (25μg): a common daily top-up

Solgar Vitamin D3 1,000 IU (25μg) softgels (250)

Solgar Vitamin D3 1,000 IU (25μg) softgels (250)
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Solgar Vitamin D3 1,000 IU (25μg) softgels (250) - features
Solgar Vitamin D3 1,000 IU (25μg) softgels (250) - qaality tests
Solgar Vitamin D3 1,000 IU (25μg) softgels (250) - directions
  • Dose: 1,000 IU (25μg)
  • How to take: 1 daily with food
  • Always check the label for dose and strength

This is a classic 'daily top-up' dose, used by people who want more than the baseline while staying well below the adult upper limit. Multiple official bodies agree on a 4,000 IU adult UL, and 1,000 IU/day sits comfortably below that ceiling.[1][4]

We found the softgel format comfortable for daily use, and the long supply helps keep the routine simple.


Vitabiotics Ultra Vitamin D 1,000 IU tablets (96)

Vitabiotics Ultra Vitamin D 1,000 IU tablets (96)
Buy Now
Vitabiotics Ultra Vitamin D 1,000 IU tablets (96) - features
Vitabiotics Ultra Vitamin D 1,000 IU tablets (96) - directions
  • Dose: 1,000 IU (25μg)
  • How to take: 1 daily
  • Always check the label for dose and strength

A straightforward one-a-day D3 tablet format, designed for routine use during the lower-sun months. The appeal is simplicity: a clear daily dose in an easy 'add it to breakfast' routine.

We found it a straightforward one-a-day tablet that fits easily into an everyday routine without feeling 'high-strength'.


Bioglan Vitamin D3 VitaGummies 1,000 IU gummies

Bioglan Vitamin D3 VitaGummies 1,000 IU gummies
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Bioglan Vitamin D3 VitaGummies 1,000 IU gummies - features
Bioglan Vitamin D3 VitaGummies 1,000 IU gummies - directions
  • Dose: 1,000 IU (25μg) per gummy
  • How to take: typically 1 gummy daily
  • Always check the label for dose and strength

Gummies exist for one reason: compliance. If tablets are a barrier, a chewable option can make 'daily vitamin D' more realistic. Evidence also shows that non-tablet delivery (including buccal/oral spray formats) can raise 25(OH)D in practice, reinforcing that the 'best' form is often the one you'll take consistently.[12][13][17]

We found this an easy, low-effort way to stay consistent, especially if tablets are the barrier rather than the dose. But as with many gummies, they are generally more expensive than tablets and softgels.


Bassetts Vitamins Adult Vitamin D Apple & Raspberry Pastilles

Bassetts Vitamins Adult Vitamin D Apple & Raspberry Pastilles
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Bassetts Vitamins Adult Vitamin D Apple & Raspberry Pastilles - features
Bassetts Vitamins Adult Vitamin D Apple & Raspberry Pastilles - benefits
Bassetts Vitamins Adult Vitamin D Apple & Raspberry Pastilles - directions
  • Dose: check label (commonly listed as 25μg / 1,000 IU per one-a-day pastille)
  • How to take: typically 1 pastille daily
  • Always check the label for dose and strength

Pastilles are another 'make it easy' format: chewable, portable, and simple. As with any chewable, the key is to read the label carefully for the dose per pastille vs. per serving and to make sure it fits your overall daily total.

We found these to be a straightforward 'one-a-day' chewable option if taste and routine help you stay consistent.


2,000 IU (50μg): a popular winter-strength choice

Vitabiotics Ultra Vitamin D 2,000 IU tablets (96)

Vitabiotics Ultra Vitamin D 2,000 IU tablets (96)
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Vitabiotics Ultra Vitamin D 2,000 IU tablets (96) - features
Vitabiotics Ultra Vitamin D 2,000 IU tablets (96) - directions
  • Dose: 2,000 IU (50μg)
  • How to take: 1 daily with food
  • Always check the label for dose and strength

2,000 IU/day is a common 'winter-strength' choice for adults seeking a higher daily intake while staying under the adult UL.[1][4] This sits in the 'stronger but still conservative' band for many people who know their sun exposure is low.

We found the tablet easy to take daily, and it's a simple step-up option if you prefer a stronger one-a-day dose over winter.


2,500 IU (62.5μg): a higher daily dose in liquid form

Natures Aid Vitamin D3 Liquid 2,500 IU

Natures Aid Vitamin D3 Liquid 2,500 IU
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Natures Aid Vitamin D3 Liquid 2,500 IU - size
Natures Aid Vitamin D3 Liquid 2,500 IU - quality testing
Natures Aid Vitamin D3 Liquid 2,500 IU - directions
  • Dose: 2,500 IU per serving (check label)
  • How to take: measured daily dose, ideally with a meal
  • Always check the label for dose and strength

Liquid vitamin D appeals to people who dislike pills or prefer flexible dosing. While there's more direct trial evidence for tablets/capsules and sprays than for any liquid format, the key remains dose and consistency - vitamin D status rises when people reliably take an effective daily dose.[6]

We found it a practical 'high-ish dose' option in a format that's easy to take consistently if tablets aren't for you.


4,000 IU (100μg): the adult upper-limit band (high strength)

The NHS and other official bodies use 4,000 IU (100 μg) as the adult upper safe limit.[1][4]

Zipvit Vitamin D3 4,000 IU tablets

Zipvit Vitamin D3 4,000 IU tablets
Buy Now
Buy Now
Zipvit Vitamin D3 4,000 IU tablets - benefits
Zipvit Vitamin D3 4,000 IU tablets - quality testing
  • Dose: 4,000 IU (100μg)
  • How to take: 1 daily with food
  • Always check the label for dose and strength

This is the 'upper-limit band' dose. It may be appropriate in some cases (for example, if advised clinically or if you've tested low and are correcting your status), but it's not the default for everyone. Evidence from high-dose trials supports the idea that 'more' isn't automatically better for bone outcomes in otherwise healthy adults.[11]

We found the tablets easy to swallow and genuinely simple to take once a day, but we'd only choose this dose for a clear reason.


VitaBright Vitamin D3 4,000 IU softgels

VitaBright Vitamin D3 4,000 IU softgels
Buy Now
VitaBright Vitamin D3 4,000 IU softgels - benefits
VitaBright Vitamin D3 4,000 IU softgels - size
VitaBright Vitamin D3 4,000 IU softgels - quality testing
VitaBright Vitamin D3 4,000 IU softgels - directions
  • Dose: 4,000 IU (100μg)
  • How to take: 1 daily with a meal
  • Always check the label for dose and strength

Same dose band, different format. A softgel may be easier to swallow than a tablet, which matters if that's what's preventing consistency. As with all 4,000 IU/day products, the 'do I actually need this much?' question matters most.[1][4]

We found the softgels comfortable to swallow, making them a good fit if high-strength tablets put you off.


BetterYou Vitamin D3 4,000 IU oral spray

BetterYou Vitamin D3 4,000 IU oral spray
Buy Now
BetterYou Vitamin D3 4,000 IU oral spray - benefits
BetterYou Vitamin D3 4,000 IU oral spray - quality testing
BetterYou Vitamin D3 4,000 IU oral spray - directions
  • Dose: 4,000 IU (100μg) per daily dose
  • How to take: 1 daily dose (spray)
  • Always check the label for dose and strength

Oral spray delivery has peer-reviewed trial evidence showing it can raise vitamin D status. This includes a crossover study comparing buccal spray with softgel capsules and a randomised, placebo-controlled trial using an oral spray solution that successfully resolved deficiency over the study period.[12][13]

We found it very easy to use and ideal if swallowing tablets is the main reason you don't take supplements consistently.


Novomins Vitamin D3 Gummies 4,000 IU

Novomins Vitamin D3 Gummies 4,000 IU
Buy Now
Novomins Vitamin D3 Gummies 4,000 IU - benefits
Novomins Vitamin D3 Gummies 4,000 IU - quality testing
Novomins Vitamin D3 Gummies 4,000 IU - directions and nutritional information
  • Dose: 4,000 IU (100μg) per daily serving
  • How to take: follow label (often 1 daily serving)
  • Always check the label for dose and strength

High-strength gummies are convenient, but label-reading matters, because 'per gummy' and 'per serving' can differ across products. If you take a high-dose gummy, it's especially important not to accidentally stack it with a multivitamin or a calcium + D product.[1]

We found them easy to take, but we'd treat the label check as non-negotiable for any high-strength gummy, softgel or tablet.


D3 + K2 combination

Zenement Vitamin D3 + K2 (2,000 IU + 150μg MK-7) softgels

Zenement Vitamin D3 + K2 (2,000 IU + 150μg MK-7) softgels
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Zenement Vitamin D3 + K2 (2,000 IU + 150μg MK-7) softgels - features
Zenement Vitamin D3 + K2 (2,000 IU + 150μg MK-7) softgels - quality testing
Zenement Vitamin D3 + K2 (2,000 IU + 150μg MK-7) softgels - directions and size
  • Dose: 2,000 IU D3 + 150μg K2 (MK-7)
  • How to take: 1 daily with food
  • Always check the label for dose and strength

This combines a mid-strength daily D3 dose with K2 (MK-7) in a single step. The rationale for pairing is explained in the dedicated D3+K2 section later in the article, including what the evidence does and doesn't show.[14][15][16]

We found the softgels easy to take with a meal and a simple way to do D3 + K2 in one step.


Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets

Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets
Buy Now
Buy Now
Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets - features and size
Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets - benefits
Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets - quality testing
Zipvit Vitamin D3 4,000 IU + Vitamin K2 MK-7 100μg tablets - why D3 and K2 together
  • Dose: 4,000 IU D3 + 100μg K2 (MK-7)
  • How to take: 1 daily with food
  • Always check the label for dose and strength

This is a high-strength combination: the adult upper limit band for D3 plus K2 in one tablet. As with any 4,000 IU/day product, treat it with care, and avoid stacking with other vitamin D-containing supplements.[1][4]

We found it a simple one-a-day combo, but it's firmly in the 'high-strength, use with care' category.


What vitamin D does in the body (why it matters)

Vitamin D acts more like a hormone than a typical vitamin. Your body converts it into active forms that help regulate calcium and phosphate, which are essential for normal bone structure, teeth, and muscle function.[1]

When vitamin D levels are very low, bones can't mineralise properly, contributing to rickets in children and osteomalacia in adults (soft bones, aches, and weakness).[3]

Simple vitamin D function infographic showing calcium and phosphate regulation supporting bones, teeth and muscle function

Vitamin D receptors are also found throughout the body (including in immune cells and muscle), which is why vitamin D is studied beyond bone health. However, the strongest, most reliable 'why take it?' remains preventing and correcting low status.[6]

Health benefits of vitamin D

Vitamin D evidence infographic comparing strongest benefits for bone and deficiency correction versus mixed evidence for immunity, mood and other outcomes

Bone, teeth and muscle support (most established benefit)

Vitamin D helps maintain normal calcium and phosphate balance, supporting bone, tooth and muscle function. This is the core, least controversial benefit. Low vitamin D status is linked to deficiency diseases such as rickets and osteomalacia.[1][3]

Falls, strength and physical function (most relevant in older adults)

Benefits appear more likely in people who start out low, and the dosing strategy matters. Some evidence supports modest benefits for physical function in specific contexts, while high-dose strategies can backfire.[3][11] Improving foot strength can also help reduce falls in older adults.

Immune function and respiratory infections (promising but nuanced evidence)

Vitamin D supplementation has shown modest reductions in acute respiratory infections in some pooled analyses, particularly when starting at very low doses and using daily or weekly dosing rather than large boluses.[8] A bolus is a very large dose taken infrequently (for example, monthly or yearly), rather than smaller, regular daily or weekly doses.

Mood, brain and 'optimisation' outcomes (mixed evidence)

Observational links exist, and mechanisms are plausible, yet trial results in broad healthy populations are often neutral or inconclusive.[5][6]

D3 vs D2: what's the difference, and which should you choose?

Photorealistic UK summer countryside walk showing brighter sunlight season when the body can make more vitamin D outdoors

Vitamin D3 (cholecalciferol) is the form your skin synthesises in sunlight, and it's the most common form used in supplements.

Both D2 and D3 can raise blood 25(OH)D, but evidence summaries commonly report that D3 tends to raise and maintain 25(OH)D more effectively than D2.[6] 25(OH)D (25-hydroxyvitamin D) is the main blood marker used to assess overall vitamin D status, reflecting your vitamin D intake from sunlight, food, and supplements over recent weeks.

Vitamin D2 (ergocalciferol) is derived from plant and fungal sources and is found in some supplements and fortified foods. D2 can work, but if you're choosing between them for everyday supplementation, most people opt for D3.[6]

Vitamin D dosing in the UK (SACN/NHS), plus other official guidelines (EU/US)

Vitamin D IU to microgram conversion chart showing 1μg equals 40IU and common doses 400IU, 1000IU, 2000IU and 4000IU

UK baseline recommendations

  • SACN recommends a Reference Nutrient Intake (RNI) of 10 μg/day (400 IU/day) for the general population aged 4+ years.[2][3] SACN is the Scientific Advisory Committee on Nutrition, the independent UK expert body that advises the government on nutrition, dietary reference values, and public health guidance (including vitamin D recommendations).

  • The NHS commonly advises taking a daily supplement in autumn and winter, and year-round for some higher-risk groups.[1] Even walkers and hikers, despite spending more time outdoors than most, may still have to supplement.

Unit conversion: 1μg vitamin D = 40 IU.[1]

UK multivitamin vitamin D guide showing typical amounts such as 5μg or 10μg and how labels may show %NRV

Upper limits (safety ceilings)

  • The NHS uses an adult upper safe limit of 100μg/day (4,000 IU/day).[1]

  • EFSA (EU) sets an adult upper limit of 100 μg/day.[4] EFSA (European Union) stands for the European Food Safety Authority, the independent EU agency that provides scientific advice on food safety, including nutrient reference values and upper safe intake levels for vitamins and minerals.

Bottle of high-strength vitamin D3 4000 IU softgel capsules showing the upper-limit adult daily dose supplement commonly used in the UK for vitamin D support

Clinical guideline perspective

The Endocrine Society (2024) emphasises that for many healthy people, the case for high-dose vitamin D specifically to prevent a wide range of diseases is uncertain, and routine screening isn't necessarily needed.[5]

When to take vitamin D (and how to store it)

When to take vitamin D infographic recommending daily dosing, taking with a meal for better absorption and choosing a format you will stick to

Take it with food (ideally including some fat)

Vitamin D is fat-soluble, and evidence summaries indicate it's best absorbed when taken with a meal or snack containing fat.[6]

Morning vs night

For most people, timing matters less than consistency does.

Storage

Store tablets and softgels in a cool, dry place away from direct light. For sprays and liquids, follow the label (cap tightly; avoid heat).

Photorealistic UK kitchen scene of taking a vitamin D supplement with breakfast to support a consistent daily routine

Safety and who should check with a clinician

Vitamin D safety infographic showing the adult upper limit of 4000IU and who should speak to a clinician before higher doses or supplement stacking

Vitamin D is fat-soluble, which means the body stores it rather than excreting excess quickly. As a result, problems tend to arise from very high doses taken over time, rather than from normal dietary intake or sensible supplementation.

The main risk is hypercalcaemia (too much calcium in the blood), which can cause nausea, weakness, confusion, and, in more serious cases, kidney complications. Staying within recognised upper limits and avoiding long-term, high-dose use without clinical oversight keeps vitamin D supplementation safe for most people.[1]

Infographic showing hidden vitamin D sources in multivitamins, calcium plus D, cod liver oil, immune blends, pregnancy vitamins and fortified foods

Quality, label accuracy and accidental overdosing of vitamin D supplements

One often overlooked risk isn't 'too much from one tablet'; it's accidental stacking. Many multivitamins already contain vitamin D (often 5-10 μg / 200-400 IU, sometimes more), and calcium supplements, immune blends, pregnancy vitamins, and cod liver oil frequently include it as well. If you then add a separate 1,000 IU, 2,000 IU, or 4,000 IU product, your true daily intake may be much higher than you realise.

Before increasing your dose, it's worth checking all the supplements you currently take and adding up their total daily vitamin D intake. This is particularly important if you're using higher-strength products.

Close-up photo of hands reading a supplement label to check vitamin D dose in IU and micrograms and avoid accidental double dosing

Label accuracy also matters: analyses of some food supplement preparations have shown discrepancies between the labelled and measured vitamin D content, underscoring the importance of choosing clearly labelled products and avoiding extreme 'mega-dose' supplements unless medically advised to do so.

A UK primary care study comparing measured vitamin D content with labelled claims found that food supplement products showed wide variation in vitamin D content compared with licensed products.[7]

Practical takeaway: keep dosing simple, know your total daily IU, and ensure it is deliberate rather than accidental. Avoid extreme 'megadose' products unless prescribed, and treat very high-dose regimens as a medical matter.[1][4][7]

Checklist infographic on vitamin D supplement quality, including clear dose labelling, batch numbers, independent testing claims and avoiding mega-dose products

Who should check with a clinician?

Check with a clinician before high-dose vitamin D if you:

  • have kidney disease, sarcoidosis, hyperparathyroidism or a history of kidney stones
  • are on medicines that affect calcium/vitamin D metabolism
  • are pregnant or breastfeeding and considering doses beyond baseline
  • plan to take 4,000 IU daily long-term (testing and re-testing is sensible)

Vitamin D benefits: what major studies and reviews show

Vitamin D infographic showing balance of evidence between supported benefits such as immune and bone pathways and risks of high doses including reduced bone density and limited fracture protection in large trials

Autoimmune disease (VITAL)

A large randomised trial reported fewer incident autoimmune diagnoses over time in the vitamin D group, suggesting that supplementation *may* reduce risk in some contexts.[9]

Acute respiratory infections (meta-analysis)

A major individual participant data meta-analysis found that vitamin D supplementation was safe and reduced the overall risk of acute respiratory tract infections, with stronger effects in people who were very deficient and in those not receiving large bolus doses.[8]

Bones and fractures (large trials)

A large trial in generally healthy adults found that vitamin D3 supplementation did not significantly reduce fractures compared with placebo.[10]

Why high doses can backfire (bone density trial)

A randomised clinical trial comparing 400, 4,000 and 10,000 IU/day reported lower volumetric bone density at higher doses in some measures.[11]

Vitamin D3 + K2: why they're combined (and when you might just use D3)

Vitamin D3 and K2 are often paired because they act along the same 'calcium pathway'. Vitamin D3 helps you absorb calcium from the gut and supports normal calcium and phosphate balance, which is central to bone and muscle function.[1][6] Vitamin K2 (often MK-7) is involved in activating vitamin K-dependent proteins such as osteocalcin (bone) and matrix Gla protein (MGP) (regulation of soft-tissue calcification).

A review summarises the biological interplay: vitamin D can increase the production of some vitamin K-dependent proteins, while vitamin K is required to activate them.[16]

That said, you don't need K2 for vitamin D to cover the basics (correcting low vitamin D and supporting bone and muscle function). Evidence for hard outcomes is mixed and depends on population, baseline status, dose, and endpoints.

In postmenopausal women, one trial reported that combined vitamin K2 + vitamin D3 therapy was associated with improvements in vertebral bone mineral density.[14] However, in elderly men with existing aortic valve calcification, a 2‑year randomised trial of MK‑7 plus vitamin D found no effect on calcification progression, providing a useful counterbalance to broad 'combo is always better' claims.[15]

Conclusion: choosing the right vitamin D for you

There isn't a single 'best' vitamin D supplement - the right choice depends on dose, form, and what you'll actually take consistently. For many people in the UK, a baseline daily dose is sufficient to reduce the risk of low vitamin D status, particularly in autumn and winter.

Others may prefer a higher daily dose, a spray, a liquid or gummy format, or a D3 + K2 combination, based on personal preference, diet, or clinical context. What matters most is that the dose is appropriate, clearly labelled, and within recognised guidance.

The evidence consistently shows that vitamin D works best when it corrects a shortfall, not when it's pushed to extremes. Staying within safe limits, avoiding accidental double-dosing from multiple products, and choosing a format you'll stick to are more important than chasing a 'perfect' supplement.

If you're considering higher doses long-term or belong to a higher-risk group, a blood test and a clinician's input can help guide your decisions. For everyone else, a simple, consistent approach to vitamin D is usually the most effective and the easiest to sustain.

Frequently Asked Questions (FAQs) on the best vitamin D supplements

What is the best vitamin D to take in the UK?

For most people, the best option is a vitamin D3 supplement at a dose you'll take consistently, often 400-2,000 IU daily.[1][2][3]

Is vitamin D3 better than vitamin D2?

Both work, but D3 is generally better at raising and maintaining 25(OH)D in most comparisons.[6]

How much vitamin D should I take daily?

UK guidance commonly uses 10 μg (400 IU) daily as a baseline.[1][2][3]

What is the maximum safe dose of vitamin D per day?

For adults, UK/EU guidance sets 100 μg (4,000 IU) daily as the upper safe limit.[1][4]

Should I take vitamin D all year in the UK?

Many people supplement in autumn and winter, and higher-risk groups may benefit year-round.[1]

What's the best time of day to take vitamin D?

Any time is fine; consistency matters most. Taking it with food can improve absorption.[6]

Are vitamin D sprays as good as tablets?

They can be effective: trials and meta-analyses show that buccal/oral spray delivery can raise 25(OH)D in practice.[12][13][17]

Are vitamin D gummies effective?

They can be useful for consistency; always check the dose per gummy or per serving and the total daily intake.

Do I need vitamin D if I eat well?

Possibly - vitamin D is difficult to obtain in high amounts from food alone, especially in winter.[1][2][3]

Should I get a vitamin D blood test?

If you're taking higher doses long-term, experiencing symptoms, or have risk factors for deficiency, testing can be useful.[5]

February 2026


Related reading:



Want to 'go deeper'?

We take evidence seriously at Walks4all. If you'd like to better understand how walking studies are designed, how results should be interpreted, and what scientific terms actually mean, explore our guides on:


References to the best vitamin D supplements

  1. NHS (n.d.) - Vitamin D. What the study shows: UK guidance on what vitamin D does, who may need supplements (especially autumn/winter), unit conversion (μg to IU), and upper safe limits including 100μg (4,000 IU) per day for adults. https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/
  2. Scientific Advisory Committee on Nutrition (SACN) (2016) - SACN vitamin D and health report (GOV.UK). What the study shows: UK evidence review underpinning the population recommendation of 10μg (400 IU) per day. https://www.gov.uk/government/publications/sacn-vitamin-d-and-health-report
  3. Scientific Advisory Committee on Nutrition (SACN) (2016) - Vitamin D and Health (full report PDF). What the study shows: Full UK report describing the RNI and evidence base for vitamin D, including considerations around dosing and safety. https://assets.publishing.service.gov.uk/media/5a804e36ed915d74e622dafa/SACN_Vitamin_D_and_Health_report.pdf
  4. EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) (2023) - Scientific opinion on the tolerable upper intake level for vitamin D. What the study shows: Establishes a tolerable upper intake level (UL) of 100μg/day (4,000 IU/day) for adults and provides ULs for younger age groups. https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2023.8145
  5. Giustina A, Bilezikian JP, Adler RA, et al. (2024) - Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows. What the study shows: International consensus on when to assess vitamin D status and practical considerations for supplementation; supports context-dependent dosing rather than blanket high-dose claims. https://pubmed.ncbi.nlm.nih.gov/38676447/
  6. NIH Office of Dietary Supplements (2025) - Vitamin D - Health Professional Fact Sheet. What the study shows: Summarises vitamin D biology, unit conversion, sources, evidence across outcomes, and notes that D3 generally raises and maintains 25(OH)D more effectively than D2 in many comparisons; also notes absorption is better with fat-containing meals. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
  7. Wan M, Patel A, Patel B, Rait G, Jones S, Shroff R (2021) - Quality and use of unlicensed vitamin D preparations in primary care in England: Retrospective review of national prescription data and laboratory analysis. What the study shows: Laboratory analysis found wide variation between measured and labelled vitamin D content in food supplement products compared with licensed preparations, highlighting the importance of label accuracy and cautious dosing. https://pubmed.ncbi.nlm.nih.gov/32803772/
  8. Martineau AR, Jolliffe DA, Hooper RL, et al. (2017) - Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. What the study shows: Vitamin D supplementation reduced risk of acute respiratory infections overall, with stronger effects in very deficient participants and with daily/weekly dosing rather than large boluses. https://www.bmj.com/content/356/bmj.i6583
  9. Hahn J, Cook NR, Alexander EK, et al. (2022) - Vitamin D and marine omega-3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial. What the study shows: Reported fewer incident autoimmune diagnoses over time in the vitamin D group; suggests possible benefit in some contexts but not definitive for all populations. https://www.bmj.com/content/376/bmj-2021-066452
  10. LeBoff MS, Chou SH, Ratliff KA, et al. (2022) - Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults. What the study shows: In generally healthy adults not selected for deficiency, vitamin D3 supplementation did not significantly reduce fractures versus placebo. https://www.nejm.org/doi/full/10.1056/NEJMoa2202106
  11. Burt LA, Billington EO, Rose MS, et al. (2019) - Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial. What the study shows: Compared 400 vs 4,000 vs 10,000 IU/day and reported lower volumetric bone density at higher doses in some measures, supporting that “more” is not always better. https://jamanetwork.com/journals/jama/fullarticle/2748796
  12. Satia MC, Mukim AG, Tibrewala KD, et al. (2015) - A randomized two way cross over study for comparison of absorption of vitamin D3 buccal spray and soft gelatin capsule formulation in healthy subjects and in patients with intestinal malabsorption. What the study shows: Buccal spray delivery increased 25(OH)D and was comparable to capsule delivery in this crossover design; includes data relevant to malabsorption. https://pubmed.ncbi.nlm.nih.gov/26514332/
  13. Todd JJ, McSorley EM, Pourshahidi LK, et al. (2017) - Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial. What the study shows: 12-week daily vitamin D3 oral spray supplementation (3,000 IU/day) resolved deficiency in wintertime athletes, supporting that spray delivery can effectively raise vitamin D status. https://pmc.ncbi.nlm.nih.gov/articles/PMC5486642/
  14. Ushiroyama T, Ikeda K, Ueki M (2002) - Effect of continuous combined therapy with vitamin K2 and vitamin D3 on bone mineral density and coagulofibrinolysis function in postmenopausal women. What the study shows: In postmenopausal women, combined K2 + D3 therapy was associated with increased vertebral bone mineral density; population-specific evidence. https://pubmed.ncbi.nlm.nih.gov/11886767/
  15. Diederichsen ACP, et al. (2022) - Vitamin K2 and D in Patients With Aortic Valve Calcification. What the study shows: In elderly men with existing aortic valve calcification, 2 years of MK-7 plus vitamin D did not influence calcification progression; useful counterbalance to “combo always helps” claims. https://pubmed.ncbi.nlm.nih.gov/35465686/
  16. van Ballegooijen AJ, Beulens JWJ (2017) - The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. What the study shows: Summarises biological interplay (vitamin D increases production of vitamin-K-dependent proteins; vitamin K activates them) and notes evidence is suggestive but not definitive for major clinical outcomes. https://pmc.ncbi.nlm.nih.gov/articles/PMC5613455/
  17. Grammatikopoulou MG, Gkiouras K, et al. (2020) - Efficacy of Vitamin D3 buccal spray supplementation: A systematic review and meta-analysis. What the study shows: Pooled evidence indicates buccal spray vitamin D3 can effectively improve vitamin D status; supports spray delivery as a valid option for some users. https://pubmed.ncbi.nlm.nih.gov/32143526/